Basic Information
ID: ALA4713359
Type: Functional
Description: Selectivity ratio of IC50 for antiproliferative activity against human NCI-H292 cells harboring wild-type EGFR to IC50 for antiproliferative activity against human NCI-H1975 cells harboring EGFR T790M/L858R mutant
Format: BAO_0000219
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4706659
Selectivity ratio of IC50 for antiproliferative activity against human NCI-H292 cells harboring wild-type EGFR to IC50 for antiproliferative activity against human NCI-H1975 cells harboring EGFR T790M/L858R mutant: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4713359
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 579.13 | 5.63 | 5.63 |
| 529.67 | 6.44 | 6.44 |
| 515.64 | 6.05 | 6.05 |
| 545.67 | 5.46 | 5.46 |
| 531.64 | 5.07 | 5.07 |
| 526.67 | 5.86 | 5.86 |
| 498.59 | 4.74 | 4.74 |
| 512.61 | 5.25 | 5.25 |
| 563.13 | 6.62 | 6.62 |
| 544.68 | 5.12 | 5.12 |
| 528.68 | 5.96 | 5.96 |
| 544.68 | 4.98 | 4.98 |
| 528.68 | 6.11 | 6.11 |