Basic Information
ID: ALA4713406
Type: Functional
Description: Induction of mitochondrial membrane potential loss in human NCI-H1975 cells harboring EGFR T790M/L858R mutant assessed as cells with intact mitochondrial membrane potential at 10 nM measured after 24 hrs by JC1 staining based fluorescence microscopic analysis (Rvb = 94.51%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H1975
Target: NCI-H1975(ALA614348)
Document: ALA4706659
Induction of mitochondrial membrane potential loss in human NCI-H1975 cells harboring EGFR T790M/L858R mutant assessed as cells with intact mitochondrial membrane potential at 10 nM measured after 24 hrs by JC1 staining based fluorescence microscopic analysis (Rvb = 94.51%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4713406
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 544.68 | 4.98 | 4.98 |