Basic Information
ID: ALA4713422
Type: Functional
Description: Antitumor activity against human NCI-H1975 cells harboring EGFR T790M/L858R mutant xenografted in nude mouse assessed as tumor volume at 15 mg/kg, po administered once daily for 7 days (Rvb = 843 mm3)
Format: BAO_0000218
Organism: Homo sapiens
Cell type: NCI-H1975
Target: NCI-H1975(ALA614348)
Document: ALA4706659
Antitumor activity against human NCI-H1975 cells harboring EGFR T790M/L858R mutant xenografted in nude mouse assessed as tumor volume at 15 mg/kg, po administered once daily for 7 days (Rvb = 843 mm3): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4713422
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 499.62 | 4.51 | 4.51 |
| 544.68 | 4.98 | 4.98 |