Basic Information
ID: ALA4713425
Type: Toxicity
Description: Toxicity in nude mouse xenografted with human NCI-H1975 cells harboring EGFR T790M/L858R mutant assessed as body weight loss at 15 mg/kg, po administered once daily for 7 days relative to control
Format: BAO_0000218
Organism: Mus musculus
Target: ADMET(ALA612558)
Document: ALA4706659
Toxicity in nude mouse xenografted with human NCI-H1975 cells harboring EGFR T790M/L858R mutant assessed as body weight loss at 15 mg/kg, po administered once daily for 7 days relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4713425
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 544.68 | 4.98 | 4.98 |