Basic Information
ID: ALA4713717
Type: Binding
Description: Inhibition of IL-6 induced STAT3 transcriptional activity in human HEK293 cells expressing SIE-luc2P preincubated for overnight followed by IL-6 stimulation and measured after 24 hr by Bio-Glo luciferase reagent based microplate reader assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4713717
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 240.21 | 2.26 | 2.26 |
| 540.49 | 1.30 | 1.30 |
| 626.58 | 1.16 | 1.16 |
| 799.90 | 3.06 | 3.06 |
| 693.76 | 3.57 | 3.57 |
| 707.78 | 3.91 | 3.91 |
| 569.53 | 2.05 | 2.05 |
| 614.61 | 1.69 | 1.69 |
| 672.65 | 1.35 | 1.35 |
| 563.52 | 2.02 | 2.02 |
| 628.59 | 1.33 | 1.33 |
| 804.81 | 1.40 | 1.40 |
| 755.85 | 3.04 | 3.04 |
| 716.70 | 1.36 | 1.36 |
| 582.57 | 2.47 | 2.47 |