Basic Information
ID: ALA4714040
Type: Binding
Description: Inhibition of HSP90-alpha (unknown origin) expressed in Escherichia coli BL21 assessed as reduction in ATPase activity at 10 uM in presence of PEP, NADH and ATP by pyruvate kinase/lactic dehydrogenase based coupled enzyme assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Heat shock protein HSP 90-alpha(ALA3880)
Document: ALA4706684
Inhibition of HSP90-alpha (unknown origin) expressed in Escherichia coli BL21 assessed as reduction in ATPase activity at 10 uM in presence of PEP, NADH and ATP by pyruvate kinase/lactic dehydrogenase based coupled enzyme assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4714040
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 585.70 | 2.54 | 2.54 |
| 343.39 | 4.74 | 4.74 |
| 295.30 | 2.67 | 2.67 |
| 309.33 | 2.71 | 2.71 |
| 335.41 | 4.00 | 4.00 |
| 427.39 | 6.33 | 6.33 |
| 278.34 | 3.54 | 3.54 |
| 347.51 | 5.59 | 5.59 |
| 285.33 | 2.77 | 2.77 |
| 321.38 | 3.96 | 3.96 |
| 309.32 | 4.07 | 4.07 |
| 271.30 | 2.72 | 2.72 |
| 302.34 | 3.49 | 3.49 |
| 321.42 | 4.30 | 4.30 |
| 401.31 | 5.04 | 5.04 |
| 319.39 | 4.79 | 4.79 |
| 369.47 | 6.02 | 6.02 |
| 297.43 | 4.35 | 4.35 |
| 333.31 | 4.02 | 4.02 |
| 359.40 | 5.31 | 5.31 |
| 328.42 | 4.78 | 4.78 |
| 377.31 | 5.09 | 5.09 |