Basic Information
ID: ALA4714159
Type: Binding
Description: Inhibition of human NET expressed in HEK293 cells assessed as reduction in ASP+ uptake incubated for 20 mins before ASP+ addition and measured after 90 mins by scintillation counting method
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4714159
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 159.23 | 1.08 | 1.08 |
| 313.40 | 3.19 | 3.19 |
| 423.54 | 3.36 | 3.36 |
| 491.54 | 4.38 | 4.38 |
| 405.46 | 2.90 | 2.90 |
| 365.40 | 1.97 | 1.97 |
| 436.58 | 4.28 | 4.28 |
| 465.62 | 4.40 | 4.40 |
| 438.56 | 2.95 | 2.95 |
| 373.52 | 3.15 | 3.15 |
| 466.61 | 3.43 | 3.43 |
| 422.55 | 3.97 | 3.97 |
| 422.55 | 3.97 | 3.97 |
| 460.58 | 3.73 | 3.73 |
| 465.62 | 4.40 | 4.40 |
| 460.58 | 3.73 | 3.73 |
| 469.64 | 4.09 | 4.09 |
| 486.62 | 4.27 | 4.27 |
| 373.52 | 3.15 | 3.15 |
| 393.45 | 2.39 | 2.39 |
| 486.62 | 4.27 | 4.27 |
| 474.61 | 3.87 | 3.87 |
| 452.58 | 3.98 | 3.98 |
| 379.42 | 2.36 | 2.36 |
| 474.61 | 4.08 | 4.08 |
| 437.57 | 3.67 | 3.67 |
| 460.58 | 3.73 | 3.73 |
| 421.57 | 4.57 | 4.57 |
| 466.61 | 3.80 | 3.80 |
| 419.53 | 3.91 | 3.91 |
| 474.61 | 3.87 | 3.87 |
| 382.45 | 2.65 | 2.65 |
| 393.45 | 2.75 | 2.75 |
| 409.45 | 1.99 | 1.99 |
| 422.55 | 3.97 | 3.97 |
| 460.58 | 3.73 | 3.73 |
| 365.44 | 2.72 | 2.72 |
| 474.61 | 3.87 | 3.87 |
| 466.61 | 3.80 | 3.80 |