Basic Information
ID: ALA4714253
Type: ADME
Description: Substrate activity at human MDR1 expressed in MDCK-II cells assessed as efflux ratio of apparent permeability across basolateral to apical over apical to basolateral membrane at 10 uM by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDCK-II
Target: P-glycoprotein 1(ALA4302)
Document: ALA4706694
Substrate activity at human MDR1 expressed in MDCK-II cells assessed as efflux ratio of apparent permeability across basolateral to apical over apical to basolateral membrane at 10 uM by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4714253
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.54 | 3.09 | 3.09 |
| 512.62 | 3.44 | 3.44 |
| 468.57 | 3.43 | 3.43 |