Basic Information
ID: ALA4714607
Type: Binding
Description: Inhibition of human full length N-terminal His-tagged GARFTase expressed in Chinese Hamster MTXRII-OuaR2-4 R2 cells assessed as reduction in THF formation using 10-CHOTHF as substrate by spectrophotometric method
Organism: Homo sapiens
Cell type: R2
Activity Charts
Bioactivity
Activity Types for Assay ALA4714607
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.45 | 0.27 | 0.27 |
| 427.42 | 0.67 | 0.67 |
| 472.52 | 2.18 | 2.18 |
| 478.55 | 2.24 | 2.24 |
| 478.55 | 2.24 | 2.24 |
| 464.53 | 1.85 | 1.85 |
| 464.53 | 1.85 | 1.85 |
| 478.55 | 2.24 | 2.24 |
| 462.48 | 1.77 | 1.77 |
| 464.53 | 1.85 | 1.85 |