ID: ALA4714676
Type: Binding
Description: Allosteric inverse agonist activity at GW9662-ligated recombinant human N-terminal His6-tagged RORgammat ligand binding domain (265 to 518 residues) expressed in Escherichia coli BL21 (DE3) assessed as reduction in coactivator, N-terminal biotinylated SRC-1 box2 peptide recruitment in presence of GW9662 incubated for 60 mins by TR-FRET assay
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4714676
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
444.80 | 5.76 | 5.76 |
461.83 | 6.32 | 6.32 |