Basic Information
ID: ALA4714709
Type: Binding
Description: Inhibition of human TRPC5 expressed in HEK293-T-REx cells assessed as decrease in riluzole-induced calcium response preincubated for 5 min followed by riluzole stimulation by Fluo-4 AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293-T-REx
Activity Charts
Bioactivity
Activity Types for Assay ALA4714709
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 484.84 | 3.06 | 3.06 |
| 423.78 | 3.59 | 3.59 |
| 441.77 | 3.73 | 3.73 |
| 408.22 | 3.36 | 3.36 |
| 437.81 | 2.96 | 2.96 |
| 401.83 | 3.27 | 3.27 |