Assay Report Card

Basic Information

ID: ALA4714724

Type: Binding

Description: Modulation of amyloid beta (1 to 42) supramolecular organization in human SH-SY5Y cells assessed as reduction in insulin resistance by measuring reduction in Abeta-42-induced IRS1 phosphorylation at Ser612 residue at 1 mM incubated for 1 hr by immunoblot analysis

Organism: Homo sapiens

Cell type: SH-SY5Y

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
179.17-3.25-3.25
221.21-3.08-3.08
259.24-3.43-3.43
259.15-3.14-3.14