Basic Information
ID: ALA4714732
Type: Binding
Description: Inhibition of recombinant human full-length His-tagged TAK1-TAB1 fusion protein (437 to 504 residues) expressed in baculovirus expression system using fluorescein-MAP2K1 as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins in presence of ATP by lanthascreen TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4714732
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 466.95 | 5.07 | 5.07 |
| 455.54 | 2.41 | 2.41 |
| 489.52 | 2.66 | 2.66 |
| 477.51 | 2.66 | 2.66 |
| 448.47 | 2.63 | 2.63 |
| 463.49 | 2.42 | 2.42 |
| 420.42 | 1.98 | 1.98 |
| 453.42 | 1.77 | 1.77 |
| 449.46 | 2.20 | 2.20 |
| 462.50 | 3.02 | 3.02 |
| 435.43 | 1.64 | 1.64 |
| 435.43 | 1.64 | 1.64 |
| 526.50 | 1.65 | 1.65 |
| 463.49 | 2.41 | 2.41 |
| 453.42 | 1.58 | 1.58 |
| 444.44 | 3.68 | 3.68 |
| 408.40 | 1.71 | 1.71 |
| 412.49 | 2.04 | 2.04 |
| 449.46 | 2.02 | 2.02 |
| 469.88 | 2.29 | 2.29 |
| 453.42 | 1.77 | 1.77 |
| 408.40 | 1.75 | 1.75 |
| 465.46 | 1.64 | 1.64 |
| 511.53 | 3.03 | 3.03 |
| 440.50 | 1.80 | 1.80 |
| 492.48 | 0.75 | 0.75 |
| 465.46 | 1.64 | 1.64 |
| 398.46 | 1.65 | 1.65 |
| 465.46 | 1.26 | 1.26 |
| 449.46 | 2.03 | 2.03 |
| 369.43 | 1.03 | 1.03 |
| 377.39 | 3.12 | 3.12 |
| 449.46 | 2.02 | 2.02 |
| 483.48 | 2.56 | 2.56 |
| 407.47 | 2.12 | 2.12 |
| 434.44 | 2.24 | 2.24 |
| 469.88 | 2.29 | 2.29 |
| 421.40 | 1.25 | 1.25 |
| 448.47 | 2.25 | 2.25 |
| 449.46 | 1.88 | 1.88 |
| 449.46 | 2.02 | 2.02 |
| 540.53 | 2.04 | 2.04 |
| 449.46 | 2.02 | 2.02 |