Basic Information
ID: ALA4714829
Type: ADME
Description: Inhibition of recombinant human His-tagged FGFR1 (308 to 731 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 01 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Fibroblast growth factor receptor 1(ALA3650)
Document: ALA4706732
Inhibition of recombinant human His-tagged FGFR1 (308 to 731 residues) cytoplasmic domain expressed in baculovirus expression system using Tyr 01 as substrate incubated for 1 hr in presence of ATP by Z'-Lyte assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4714829
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.57 | 1.48 | 1.48 |
| 489.36 | 5.56 | 5.56 |
| 502.36 | 5.28 | 5.28 |
| 505.36 | 4.77 | 4.77 |
| 477.35 | 5.04 | 5.04 |
| 474.35 | 5.37 | 5.37 |
| 460.32 | 5.32 | 5.32 |
| 507.35 | 5.85 | 5.85 |
| 511.79 | 5.61 | 5.61 |
| 525.41 | 5.32 | 5.32 |
| 514.37 | 5.45 | 5.45 |
| 473.36 | 5.48 | 5.48 |