Basic Information
ID: ALA4714842
Type: Functional
Description: Positive allosteric modulation of recombinant human muscarinic M1 receptor co-expressing pCRE-Luc reporter gene in CHO cells assessed as stimulation of luciferase activity in presence of acetylcholine substrate measured after 4 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Muscarinic acetylcholine receptor M1(ALA216)
Document: ALA4706733
Positive allosteric modulation of recombinant human muscarinic M1 receptor co-expressing pCRE-Luc reporter gene in CHO cells assessed as stimulation of luciferase activity in presence of acetylcholine substrate measured after 4 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4714842
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.48 | 3.49 | 3.49 |
| 456.55 | 4.03 | 4.03 |
| 440.55 | 4.33 | 4.33 |
| 429.52 | 3.36 | 3.36 |
| 414.30 | 3.60 | 3.60 |
| 415.50 | 3.23 | 3.23 |
| 444.51 | 4.16 | 4.16 |
| 426.52 | 4.02 | 4.02 |
| 469.55 | 3.12 | 3.12 |
| 440.55 | 4.33 | 4.33 |
| 415.50 | 3.23 | 3.23 |
| 451.53 | 3.89 | 3.89 |
| 426.52 | 4.02 | 4.02 |
| 460.97 | 4.67 | 4.67 |