Basic Information
ID: ALA4714848
Type: Binding
Description: Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 80 mins by ADP-Glo reagent based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4714848
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 534.70 | 3.77 | 3.77 |
| 562.76 | 4.55 | 4.55 |
| 512.68 | 4.04 | 4.04 |
| 566.65 | 4.43 | 4.43 |
| 548.66 | 4.29 | 4.29 |
| 534.70 | 3.30 | 3.30 |