Basic Information
ID: ALA4715192
Type: Functional
Description: Antagonist activity in CXCR1 (unknown origin) expressed in human HEK293 cells co-expressing Galpha16 assessed as reduction in calcium immobilization pretreated with Fluo-4AM for 45 mins followed by compound addition and measured after 10 mins by Fluo-4AM dye based fluorescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4715192
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 397.43 | 2.90 | 2.90 |
| 421.91 | 2.74 | 2.74 |
| 413.93 | 3.07 | 3.07 |
| 413.93 | 3.07 | 3.07 |
| 373.86 | 2.29 | 2.29 |
| 387.89 | 2.54 | 2.54 |
| 387.89 | 2.68 | 2.68 |
| 359.84 | 1.90 | 1.90 |
| 442.32 | 3.52 | 3.52 |
| 373.86 | 2.29 | 2.29 |
| 442.32 | 3.52 | 3.52 |
| 523.01 | 3.37 | 3.37 |
| 421.91 | 2.74 | 2.74 |
| 345.81 | 1.51 | 1.51 |
| 423.88 | 2.10 | 2.10 |
| 331.78 | 1.13 | 1.13 |
| 292.30 | 1.90 | 1.90 |
| 338.37 | 1.73 | 1.73 |
| 407.88 | 2.87 | 2.87 |
| 345.81 | 1.51 | 1.51 |
| 373.86 | 2.29 | 2.29 |
| 425.87 | 3.01 | 3.01 |
| 312.29 | 1.94 | 1.94 |
| 442.32 | 3.52 | 3.52 |
| 345.81 | 1.51 | 1.51 |