Assay Report Card

Basic Information

ID: ALA4715506

Type: Functional

Description: Invivo protac activity at CRBN/STAT6 degradation in SCID mouse xenografted with human MOLM16 cells assessed as reduction in STAT6 in tumor tissue at 50 mg/kg, iv measured after 24 hrs by immunoblotting analysis

Organism: Mus musculus

Strain: SCID

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1158.17