Basic Information
ID: ALA4715510
Type: ADME
Description: Drug uptake in SCID mouse xenografted with human MOLM16 cells assessed as (2-(((5S,8S,10aR)-8-(((S)-5-amino-1-(benzhydrylamino)-1,5-dioxopentan-2-yl)carbamoyl)-3-(8-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oct-7-yno yl)-6-oxodecahydropyrrolo[1,2-a][1,5]diazocin-5-yl)carbamoyl)-1H-indole-5-carbonyl)phosphonic acid level in plasma at 50 mg/kg, iv measured after 24 hrs by LC-MS/MS
Organism: Mus musculus
Strain: SCID
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA4715510
Drug uptake
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1158.17 |