Basic Information
ID: ALA4716074
Type: Binding
Description: Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as inhibition of antiIgM-induced Akt phosphorylation at ser 473 residue preincubated for 45 mins followed by antiIgM stimulation and measured after 15 mins by immunostaining based flow cytometry analysis
Organism: Mus musculus
Strain: Balb/c
Cell type: B cell
Activity Charts
Bioactivity
Activity Types for Assay ALA4716074
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 373.40 | 3.58 | 3.58 |
| 392.37 | 3.12 | 3.12 |
| 374.38 | 2.98 | 2.98 |
| 409.38 | 3.86 | 3.86 |