Basic Information
ID: ALA4716189
Type: Binding
Description: Inhibition of crizotinib-resistant ALK L1196M mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: ALK tyrosine kinase receptor(ALA4247)
Document: ALA4715694
Inhibition of crizotinib-resistant ALK L1196M mutant (unknown origin) using peptide substrate incubated for 30 mins in presence of ATP by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4716189
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 558.15 | 6.36 | 6.36 |
| 567.09 | 3.37 | 3.37 |
| 573.12 | 4.25 | 4.25 |
| 488.01 | 4.45 | 4.45 |
| 530.09 | 5.62 | 5.62 |
| 567.09 | 3.37 | 3.37 |
| 546.05 | 3.68 | 3.68 |
| 502.04 | 4.80 | 4.80 |
| 483.98 | 5.36 | 5.36 |
| 530.05 | 4.71 | 4.71 |
| 559.14 | 4.73 | 4.73 |
| 546.05 | 3.68 | 3.68 |
| 516.07 | 5.23 | 5.23 |
| 502.04 | 4.80 | 4.80 |
| 559.09 | 4.90 | 4.90 |
| 643.98 | 4.94 | 4.94 |
| 530.05 | 4.71 | 4.71 |
| 532.07 | 4.16 | 4.16 |
| 516.07 | 5.19 | 5.19 |
| 573.12 | 4.25 | 4.25 |
| 486.00 | 4.78 | 4.78 |
| 530.09 | 5.48 | 5.48 |
| 559.14 | 4.73 | 4.73 |
| 488.01 | 4.45 | 4.45 |
| 516.07 | 5.19 | 5.19 |
| 559.09 | 4.90 | 4.90 |
| 532.07 | 4.16 | 4.16 |