Basic Information
ID: ALA4716983
Type: Binding
Description: Inhibition of BET in human THP-1 cells assessed as suppression of LPS-induced IL-6 release measured after 16 hrs by chemiluminescence ELISA
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA4716983
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 301.35 | 4.22 | 4.22 |
| 367.84 | 3.58 | 3.58 |
| 422.49 | 5.14 | 5.14 |
| 402.91 | 3.89 | 3.89 |
| 391.87 | 4.07 | 4.07 |
| 324.81 | 4.31 | 4.31 |
| 310.79 | 3.92 | 3.92 |
| 395.89 | 3.99 | 3.99 |
| 407.48 | 5.42 | 5.42 |
| 438.49 | 4.03 | 4.03 |
| 393.45 | 4.86 | 4.86 |
| 405.89 | 4.37 | 4.37 |
| 416.92 | 5.13 | 5.13 |
| 324.82 | 4.48 | 4.48 |
| 416.92 | 5.13 | 5.13 |
| 431.93 | 4.85 | 4.85 |
| 415.93 | 5.85 | 5.85 |
| 390.88 | 4.32 | 4.32 |
| 438.49 | 4.13 | 4.13 |
| 416.92 | 5.13 | 5.13 |