Basic Information
ID: ALA4717444
Type: ADME
Description: Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrate by MUX-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4715723
Inhibition of human liver microsomes CYP2D6 using dextromethorphan as substrate by MUX-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4717444
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.41 | 5.40 | 5.40 |
| 402.89 | 4.95 | 4.95 |
| 422.85 | 5.29 | 5.29 |
| 403.87 | 5.10 | 5.10 |
| 454.41 | 5.40 | 5.40 |
| 451.45 | 5.72 | 5.72 |
| 439.40 | 5.04 | 5.04 |
| 414.29 | 5.48 | 5.48 |
| 404.86 | 5.15 | 5.15 |
| 404.86 | 5.15 | 5.15 |
| 379.85 | 4.83 | 4.83 |
| 437.43 | 5.47 | 5.47 |
| 423.40 | 5.16 | 5.16 |
| 453.42 | 5.35 | 5.35 |