Basic Information
ID: ALA4717574
Type: ADME
Description: Inhibition of CYP2D6 (unknown origin) expressed in insect cells assessed as reduction in 1'-hydroxybufuralol formation using bufuralol as substrate at 10 uM incubated for 60 mins by LC/MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4715727
Inhibition of CYP2D6 (unknown origin) expressed in insect cells assessed as reduction in 1'-hydroxybufuralol formation using bufuralol as substrate at 10 uM incubated for 60 mins by LC/MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4717574
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.27 | 1.52 | 1.52 |
| 381.28 | 1.91 | 1.91 |
| 367.25 | 1.52 | 1.52 |
| 383.70 | 2.03 | 2.03 |
| 393.29 | 2.05 | 2.05 |
| 367.70 | 2.80 | 2.80 |
| 395.30 | 2.30 | 2.30 |
| 399.29 | 3.19 | 3.19 |
| 381.27 | 1.91 | 1.91 |
| 381.28 | 1.91 | 1.91 |
| 381.73 | 3.19 | 3.19 |
| 395.30 | 2.30 | 2.30 |
| 353.68 | 2.41 | 2.41 |
| 409.29 | 1.29 | 1.29 |