Potency index, ratio of mexiletine EC50 to test compound EC50 for negative inotropic activity in guinea pig left atrium assessed as decrease in develo...

Basic Information

ID: ALA4717687

Type: ADME

Description: Potency index, ratio of mexiletine EC50 to test compound EC50 for negative inotropic activity in guinea pig left atrium assessed as decrease in developed tension

Format: BAO_0000221

Organism: Cavia porcellus

Tissue: Left cardiac atrium

Target:  Left atrium(ALA2367407)

Document:  ALA4715731

Potency index, ratio of mexiletine EC50 to test compound EC50 for negative inotropic activity in guinea pig left atrium assessed as decrease in developed tension: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
291.823.253.25