Basic Information
ID: ALA4718228
Type: Binding
Description: Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysis
Format: BAO_0000357
Organism: Trypanosoma cruzi
Target: Cruzipain(ALA3563)
Document: ALA4715737
Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4718228
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.23 | 3.07 | 3.07 |
| 286.20 | 2.81 | 2.81 |
| 362.30 | 4.96 | 4.96 |
| 386.32 | 5.80 | 5.80 |
| 400.35 | 6.11 | 6.11 |
| 416.34 | 5.81 | 5.81 |
| 479.24 | 6.87 | 6.87 |
| 431.32 | 5.71 | 5.71 |
| 420.76 | 6.45 | 6.45 |
| 404.31 | 5.94 | 5.94 |
| 400.35 | 6.11 | 6.11 |
| 455.21 | 7.11 | 7.11 |
| 455.21 | 7.11 | 7.11 |
| 430.37 | 5.24 | 5.24 |
| 462.42 | 6.68 | 6.68 |
| 436.38 | 6.95 | 6.95 |
| 462.42 | 7.47 | 7.47 |
| 431.32 | 5.71 | 5.71 |