Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence ...

Basic Information

ID: ALA4718478

Type: Binding

Description: Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence plate reader assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293T

Target: Histone deacetylase 1(ALA325)

Document: ALA4715745

Inhibition of human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence plate reader assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4718478

IC50

Total(9)

Parent Molecular Weight	ALogP	Polar Surface Area
540.71	1.43	1.43
562.71	1.11	1.11
528.70	0.92	0.92
498.63	0.41	0.41
528.70	0.92	0.92
486.62	-0.11	-0.11
472.59	-0.50	-0.50
562.71	1.11	1.11
486.62	-0.11	-0.11

Parent Molecular Weight

ALogP

Polar Surface Area

540.71

1.43

562.71

1.11

528.70

0.92

498.63

0.41

528.70

0.92

486.62

-0.11

472.59

-0.50