Basic Information
ID: ALA4718480
Type: Unassigned
Description: Selectivity index, ratio of IC50 for mouse HDAC6 expressed in 293T cells to IC50 for human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence plate reader assay
Format: BAO_0000219
Target: Unchecked(ALA612545)
Document: ALA4715745
Selectivity index, ratio of IC50 for mouse HDAC6 expressed in 293T cells to IC50 for human HDAC1 expressed in 293T cells using Ac-KGLGK(Ac)-MCA as substrate incubated for 30 mins in presence of 0.1 mM DTT by fluorescence plate reader assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4718480
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 540.71 | 1.43 | 1.43 |
| 562.71 | 1.11 | 1.11 |
| 528.70 | 0.92 | 0.92 |
| 498.63 | 0.41 | 0.41 |
| 528.70 | 0.92 | 0.92 |
| 486.62 | -0.11 | -0.11 |
| 472.59 | -0.50 | -0.50 |
| 562.71 | 1.11 | 1.11 |
| 486.62 | -0.11 | -0.11 |