Basic Information
ID: ALA4718838
Type: Binding
Description: Inhibition of human EGFR at 100 nM using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma33P]ATP by radiometric HotSpot assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4718838
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 374.44 | 4.82 | 4.82 |
| 408.48 | 3.17 | 3.17 |
| 453.52 | 3.15 | 3.15 |
| 315.38 | 4.19 | 4.19 |
| 501.64 | 2.77 | 2.77 |
| 407.50 | 4.17 | 4.17 |
| 371.44 | 4.76 | 4.76 |
| 380.40 | 5.40 | 5.40 |
| 372.47 | 5.59 | 5.59 |
| 378.41 | 3.40 | 3.40 |
| 430.56 | 3.42 | 3.42 |
| 448.55 | 3.56 | 3.56 |
| 448.55 | 3.56 | 3.56 |
| 361.41 | 3.17 | 3.17 |
| 393.47 | 3.45 | 3.45 |
| 344.42 | 3.78 | 3.78 |
| 387.44 | 3.91 | 3.91 |
| 444.58 | 4.46 | 4.46 |
| 387.44 | 2.80 | 2.80 |
| 388.47 | 4.56 | 4.56 |
| 423.50 | 3.14 | 3.14 |
| 417.47 | 3.74 | 3.74 |
| 357.42 | 3.90 | 3.90 |
| 374.44 | 4.17 | 4.17 |
| 403.44 | 2.88 | 2.88 |
| 500.65 | 4.35 | 4.35 |
| 437.53 | 4.18 | 4.18 |
| 358.40 | 4.50 | 4.50 |
| 331.38 | 3.17 | 3.17 |
| 474.61 | 3.77 | 3.77 |
| 495.61 | 2.91 | 2.91 |
| 358.45 | 5.20 | 5.20 |
| 344.42 | 4.16 | 4.16 |
| 460.58 | 3.43 | 3.43 |
| 502.62 | 3.20 | 3.20 |
| 378.41 | 3.40 | 3.40 |
| 331.38 | 3.17 | 3.17 |
| 357.42 | 3.90 | 3.90 |
| 404.47 | 3.93 | 3.93 |
| 363.44 | 3.78 | 3.78 |
| 410.42 | 5.03 | 5.03 |
| 392.48 | 4.20 | 4.20 |
| 398.39 | 5.70 | 5.70 |