Basic Information
ID: ALA4718842
Type: ADME
Description: Metabolic stability in pooled human liver microsomes assessed as Clearance at 3 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4718842
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 390.44 | 3.27 | 3.27 |
| 360.42 | 3.26 | 3.26 |
| 453.52 | 3.15 | 3.15 |
| 501.64 | 2.77 | 2.77 |
| 407.50 | 4.17 | 4.17 |
| 380.40 | 5.40 | 5.40 |
| 378.41 | 3.40 | 3.40 |
| 448.55 | 3.56 | 3.56 |
| 448.55 | 3.56 | 3.56 |
| 361.41 | 3.17 | 3.17 |
| 344.42 | 3.78 | 3.78 |
| 444.58 | 4.46 | 4.46 |
| 387.44 | 2.80 | 2.80 |
| 388.47 | 4.56 | 4.56 |
| 423.50 | 3.14 | 3.14 |
| 374.44 | 4.17 | 4.17 |
| 403.44 | 2.88 | 2.88 |
| 500.65 | 4.35 | 4.35 |
| 437.53 | 4.18 | 4.18 |
| 330.39 | 3.77 | 3.77 |
| 360.42 | 3.78 | 3.78 |
| 474.61 | 3.77 | 3.77 |
| 495.61 | 2.91 | 2.91 |
| 344.42 | 4.16 | 4.16 |
| 460.58 | 3.43 | 3.43 |
| 502.62 | 3.20 | 3.20 |
| 378.41 | 3.40 | 3.40 |
| 363.44 | 3.78 | 3.78 |
| 410.42 | 5.03 | 5.03 |