Basic Information
ID: ALA4718894
Type: ADME
Description: Substrate activity at human LAT1 expressed in HEK293-T-Rex cells assessed as [3H]-gabapentin efflux preincubated for 30 mins followed by treated at 200 uM by scintillation counting trans-stimulation assay relative to control
Organism: Homo sapiens
Cell type: HEK293-T-REx
Activity Charts
Bioactivity
Activity Types for Assay ALA4718894
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 75.07 | -0.97 | -0.97 |
| 149.21 | 0.15 | 0.15 |
| 181.19 | 0.35 | 0.35 |
| 165.19 | 0.64 | 0.64 |
| 131.17 | 0.44 | 0.44 |
| 204.23 | 1.12 | 1.12 |
| 180.21 | 0.06 | 0.06 |
| 90.08 | -1.55 | -1.55 |
| 196.21 | -0.23 | -0.23 |
| 174.20 | -1.34 | -1.34 |
| 219.24 | 0.54 | 0.54 |
| 131.18 | 0.44 | 0.44 |
| 182.65 | -0.13 | -0.13 |
| 242.30 | -0.37 | -0.37 |
| 258.30 | -0.66 | -0.66 |
| 200.69 | -0.43 | -0.43 |
| 182.65 | -0.13 | -0.13 |
| 196.68 | 0.04 | 0.04 |
| 166.65 | -0.15 | -0.15 |
| 189.22 | 0.44 | 0.44 |