Basic Information
ID: ALA4718896
Type: Binding
Description: Inhibition of human LAT1 expressed in HEK293-T-Rex cells assessed as inhibition of [3H]-gabapentin uptake by scintillation counting cis-inhibition assay relative to BCH inhibition (RV = 100%)
Organism: Homo sapiens
Cell type: HEK293-T-REx
Activity Charts
Bioactivity
Activity Types for Assay ALA4718896
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 75.07 | -0.97 | -0.97 |
| 149.21 | 0.15 | 0.15 |
| 131.17 | 0.44 | 0.44 |
| 90.08 | -1.55 | -1.55 |
| 131.18 | 0.44 | 0.44 |
| 182.65 | -0.13 | -0.13 |
| 200.69 | -0.43 | -0.43 |
| 182.65 | -0.13 | -0.13 |
| 196.68 | 0.04 | 0.04 |
| 166.65 | -0.15 | -0.15 |