Basic Information
ID: ALA4719151
Type: Binding
Description: Inhibition of recombinant human N-terminal His-tagged Pin1 expressed in Escherichia coli BL21 using Suc-Ala-Glu-Pro-Phe-4-nitroanilide as substrate incubated for 10 mins followed by substrate addition and measured for 90 sec by spectrophotometry
Format: BAO_0000019
Organism: Homo sapiens
Target: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(ALA2288)
Document: ALA4715774
Inhibition of recombinant human N-terminal His-tagged Pin1 expressed in Escherichia coli BL21 using Suc-Ala-Glu-Pro-Phe-4-nitroanilide as substrate incubated for 10 mins followed by substrate addition and measured for 90 sec by spectrophotometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4719151
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.38 | 3.49 | 3.49 |
| 376.39 | 3.89 | 3.89 |
| 451.44 | 4.50 | 4.50 |
| 469.43 | 4.64 | 4.64 |
| 447.47 | 4.67 | 4.67 |
| 467.89 | 5.02 | 5.02 |
| 489.51 | 5.31 | 5.31 |
| 413.46 | 3.61 | 3.61 |
| 467.89 | 5.02 | 5.02 |
| 459.48 | 4.88 | 4.88 |
| 463.47 | 4.37 | 4.37 |
| 475.48 | 5.00 | 5.00 |
| 501.44 | 5.38 | 5.38 |
| 447.47 | 4.67 | 4.67 |
| 451.44 | 4.50 | 4.50 |
| 433.45 | 4.36 | 4.36 |
| 463.47 | 4.37 | 4.37 |
| 501.44 | 5.38 | 5.38 |
| 458.46 | 4.24 | 4.24 |
| 537.41 | 5.54 | 5.54 |
| 473.51 | 5.19 | 5.19 |
| 465.46 | 4.81 | 4.81 |
| 470.31 | 4.81 | 4.81 |
| 465.46 | 4.81 | 4.81 |