Basic Information
ID: ALA4719349
Type: Functional
Description: Antagonist activity at human MOR transfected in CHO cells co-transfected with Gqi5 assessed as inhibition of DAMGO-induced calcium mobilization incubated for 15 mins prior to DAMGO addition and measured for 90 secs by Fluo-4AM dye based fluorescence analysis
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4719349
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.41 | 1.53 | 1.53 |
| 671.79 | -0.38 | -0.38 |
| 699.85 | 0.40 | 0.40 |
| 727.90 | 1.18 | 1.18 |
| 1197.48 | ||
| 1197.48 | ||
| 1225.53 | ||
| 1169.43 |