Basic Information
ID: ALA4719351
Type: Functional
Description: Antagonist activity at CCR5 receptor in human MOLT4 cells transfected with Gqi5 assessed as inhibition of RANTES-induced calcium mobilization incubated for 15 mins prior to RANTES addition and measured for 120 secs by Fluo-4AM dye based fluorescence analysis
Organism: Homo sapiens
Cell type: MOLT-4
Activity Charts
Bioactivity
Activity Types for Assay ALA4719351
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.68 | 5.95 | 5.95 |
| 1197.48 | ||
| 1197.48 | ||
| 914.15 | 5.63 | 5.63 |
| 1225.53 | ||
| 886.10 | 4.85 | 4.85 |
| 1169.43 | ||
| 886.10 | 4.85 | 4.85 |
| 858.04 | 4.07 | 4.07 |