Assay Report Card

Basic Information

ID: ALA4719354

Type: Binding

Description: Binding affinity to CCR5-hMOR heterodimer in CHO cells co-expressing CD4 and luciferase reporter assessed as inhibition of CD4-gp120 complex interaction with receptor dimer by measuring inhibition of cell-cell fusion process at 3000 nM measured after co-incubation of CHO cells with HEK293 cells expressing HIV-1 gp120 and T7 polymerase in presence of compound for 18 hrs by luciferase based luminescence assay

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1197.48