Basic Information
ID: ALA4719362
Type: Binding
Description: Binding affinity to CCR5-hMOR heterodimer in CHO cells co-expressing CD4 and luciferase reporter assessed as inhibition of CD4-gp120 complex interaction with receptor dimer by measuring inhibition of cell-cell fusion process at 3000 nM measured after co-incubation of CHO cells with HEK293 cells expressing HIV-1 gp120 and T7 polymerase in presence of compound and morphine for 18 hrs by luciferase based luminescence assay
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA4719362
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1197.48 |