Basic Information
ID: ALA4719638
Type: Binding
Description: Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs by luciferase reporter gene assay relative to 2',3'-cGAMP
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: Stimulator of interferon genes protein(ALA4523377)
Document: ALA4715794
Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs by luciferase reporter gene assay relative to 2',3'-cGAMP: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4719638
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 282.30 | 3.19 | 3.19 |
| 659.40 | -1.92 | -1.92 |
| 695.52 | 2.32 | 2.32 |
| 677.53 | 2.37 | 2.37 |
| 645.39 | 0.49 | 0.49 |
| 659.40 | -1.51 | -1.51 |
| 691.54 | 0.36 | 0.36 |
| 659.40 | -1.51 | -1.51 |
| 627.40 | 0.55 | 0.55 |
| 659.40 | -1.51 | -1.51 |
| 663.38 | 0.44 | 0.44 |
| 645.39 | 0.49 | 0.49 |