Basic Information
ID: ALA4719951
Type: Functional
Description: Antagonist activity at human recombinant mGlu3 stably expressed in golden hamster AV12 cell membrane co-expressing Galpha15 assessed as assessed as reduction in glutamate-induced calcium influx incubated for 90 to 120 min by Fluo-4-AM dye based FLIPR assay
Organism: Homo sapiens
Cell type: AV12
Subcellular Fraction: Cell membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA4719951
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 353.37 | 2.82 | 2.82 |
| 395.81 | 0.78 | 0.78 |