Assay Report Card

Basic Information

ID: ALA4719953

Type: Functional

Description: Antagonist activity at human recombinant mGlu1 stably expressed in golden hamster AV12 cell membrane co-expressing Gq assessed as reduction in glutamate-induced calcium influx incubated for 90 to 120 min by Fluo-4-AM dye based FLIPR assay

Organism: Homo sapiens

Cell type: AV12

Subcellular Fraction: Cell membrane

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
395.810.780.78