Basic Information
ID: ALA4720019
Type: Binding
Description: Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells using ABLtide as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr in presence of ATP by kinase-Glo luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Bcr/Abl fusion protein(ALA2096618)
Document: ALA4715809
Inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells using ABLtide as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr in presence of ATP by kinase-Glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4720019
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.54 | 4.35 | 4.35 |
| 424.46 | 4.15 | 4.15 |
| 462.44 | 5.16 | 5.16 |
| 412.43 | 4.28 | 4.28 |
| 412.43 | 4.28 | 4.28 |
| 412.43 | 4.28 | 4.28 |
| 462.44 | 5.16 | 5.16 |
| 520.64 | 4.28 | 4.28 |
| 424.46 | 4.15 | 4.15 |
| 428.88 | 4.80 | 4.80 |
| 462.44 | 5.16 | 5.16 |
| 493.57 | 3.97 | 3.97 |
| 493.57 | 3.97 | 3.97 |
| 506.61 | 3.89 | 3.89 |
| 422.49 | 4.71 | 4.71 |