Basic Information
ID: ALA4720023
Type: Binding
Description: Potency index, ratio of staurosporine IC50 to test compound IC50 for inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells using ABLtide as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr in presence of ATP by kinase-Glo luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Bcr/Abl fusion protein(ALA2096618)
Document: ALA4715809
Potency index, ratio of staurosporine IC50 to test compound IC50 for inhibition of BCR (unknown origin)/recombinant human N-terminal His-tagged ABL1 (27 to end residues) expressed in baculovirus infected Sf9 cells using ABLtide as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr in presence of ATP by kinase-Glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4720023
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.44 | 5.16 | 5.16 |