Basic Information
ID: ALA4721173
Type: Binding
Description: Inhibition of recombinant human N-terminal GST tagged EGFR L858R/T790M double mutant (669 to 1210 residues) expressed in insect expression system using peptide as substrate incubated for 2 hrs followed by substrate addition and measured after 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4721173
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.95 | 4.39 | 4.39 |
| 485.95 | 4.39 | 4.39 |
| 494.98 | 4.55 | 4.55 |
| 499.62 | 4.51 | 4.51 |
| 598.99 | 5.57 | 5.57 |