Basic Information
ID: ALA4721244
Type: Binding
Description: Inhibition of recombinant full-length LRRK2 (unknown origin) expressed in SH-SY5Y cells assessed as reduction in Ser935 phosphorylation after 60 mins by Alpha Screen assay
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA4721244
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.46 | 2.97 | 2.97 |
| 399.45 | 2.61 | 2.61 |
| 425.49 | 3.36 | 3.36 |
| 450.54 | 3.28 | 3.28 |
| 446.46 | 3.09 | 3.09 |
| 367.41 | 2.57 | 2.57 |
| 413.45 | 3.68 | 3.68 |
| 436.52 | 3.03 | 3.03 |
| 438.53 | 3.28 | 3.28 |
| 410.48 | 2.50 | 2.50 |
| 380.45 | 2.49 | 2.49 |
| 423.52 | 2.55 | 2.55 |
| 425.49 | 3.36 | 3.36 |
| 350.30 | 2.77 | 2.77 |
| 411.46 | 2.97 | 2.97 |
| 436.52 | 3.03 | 3.03 |
| 424.51 | 2.89 | 2.89 |
| 398.44 | 2.63 | 2.63 |
| 414.90 | 3.14 | 3.14 |
| 411.46 | 2.97 | 2.97 |
| 397.44 | 2.58 | 2.58 |
| 409.45 | 2.58 | 2.58 |