Basic Information
ID: ALA4721796
Type: Binding
Description: Covalent binding affinity to CRYZ at Cys45 residue in human NCI-H358 cells assessed as log2 H/L ratio at 10 uM pretreated for 3 hrs followed by N-(((6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl)methyl)-2-hydroxyacetamide treatment for 3 hrs by competitive TMT click chemistry pull-down experiment based LC-MS/MS analysis
Organism: Homo sapiens
Cell type: NCI-H358
Activity Charts
Bioactivity
Activity Types for Assay ALA4721796
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.84 | 3.77 | 3.77 |