ID: ALA4722341
Type: Functional
Description: Antagonist activity at human P2X2 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced intracellular calcium influx at 10 uM preincubated for 20 mins followed by ATP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay relative to control
Organism: Homo sapiens
Cell type: 1321N1
Bioactivity
Activity Types for Assay ALA4722341
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
357.79 | 3.93 | 3.93 |
1429.19 | ||
477.29 | 4.38 | 4.38 |
416.39 | 3.75 | 3.75 |
375.38 | 4.41 | 4.41 |
432.84 | 4.27 | 4.27 |
432.84 | 4.27 | 4.27 |
412.42 | 3.92 | 3.92 |
412.42 | 3.92 | 3.92 |
428.42 | 3.62 | 3.62 |
375.38 | 4.41 | 4.41 |
432.84 | 4.27 | 4.27 |
411.44 | 3.96 | 3.96 |
375.38 | 4.41 | 4.41 |
375.38 | 4.41 | 4.41 |
432.84 | 4.27 | 4.27 |
389.41 | 4.59 | 4.59 |
412.42 | 3.92 | 3.92 |
414.91 | 4.38 | 4.38 |
411.44 | 3.96 | 3.96 |
375.38 | 4.41 | 4.41 |
375.38 | 4.41 | 4.41 |
375.38 | 4.41 | 4.41 |
466.39 | 4.63 | 4.63 |
432.84 | 4.27 | 4.27 |
412.42 | 3.92 | 3.92 |
440.43 | 3.82 | 3.82 |
467.29 | 4.92 | 4.92 |
454.46 | 4.21 | 4.21 |
403.44 | 4.68 | 4.68 |
389.41 | 4.59 | 4.59 |
375.38 | 4.41 | 4.41 |
403.44 | 4.68 | 4.68 |
398.40 | 3.61 | 3.61 |
389.41 | 4.59 | 4.59 |
416.39 | 3.75 | 3.75 |
403.44 | 4.68 | 4.68 |