Assay Report Card

Basic Information

ID: ALA4722341

Type: Functional

Description: Antagonist activity at human P2X2 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced intracellular calcium influx at 10 uM preincubated for 20 mins followed by ATP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay relative to control

Organism: Homo sapiens

Cell type: 1321N1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
357.793.933.93
1429.19
477.294.384.38
416.393.753.75
375.384.414.41
432.844.274.27
432.844.274.27
412.423.923.92
412.423.923.92
428.423.623.62
375.384.414.41
432.844.274.27
411.443.963.96
375.384.414.41
375.384.414.41
432.844.274.27
389.414.594.59
412.423.923.92
414.914.384.38
411.443.963.96
375.384.414.41
375.384.414.41
375.384.414.41
466.394.634.63
432.844.274.27
412.423.923.92
440.433.823.82
467.294.924.92
454.464.214.21
403.444.684.68
389.414.594.59
375.384.414.41
403.444.684.68
398.403.613.61
389.414.594.59
416.393.753.75
403.444.684.68