Basic Information
ID: ALA4722348
Type: Functional
Description: Antagonist activity at human P2Y1 receptor expressed in human 1321N1 cells assessed as inhibition of ADP-induced intracellular calcium influx at 10 uM preincubated for 20 mins followed by ADP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay
Organism: Homo sapiens
Cell type: 1321N1
Activity Charts
Bioactivity
Activity Types for Assay ALA4722348
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 477.29 | 4.38 | 4.38 |
| 416.39 | 3.75 | 3.75 |
| 375.38 | 4.41 | 4.41 |
| 432.84 | 4.27 | 4.27 |
| 432.84 | 4.27 | 4.27 |
| 412.42 | 3.92 | 3.92 |
| 412.42 | 3.92 | 3.92 |
| 428.42 | 3.62 | 3.62 |
| 375.38 | 4.41 | 4.41 |
| 432.84 | 4.27 | 4.27 |
| 411.44 | 3.96 | 3.96 |
| 375.38 | 4.41 | 4.41 |
| 392.44 | 3.89 | 3.89 |
| 375.38 | 4.41 | 4.41 |
| 432.84 | 4.27 | 4.27 |
| 389.41 | 4.59 | 4.59 |
| 412.42 | 3.92 | 3.92 |
| 414.91 | 4.38 | 4.38 |
| 411.44 | 3.96 | 3.96 |
| 375.38 | 4.41 | 4.41 |
| 375.38 | 4.41 | 4.41 |
| 375.38 | 4.41 | 4.41 |
| 466.39 | 4.63 | 4.63 |
| 432.84 | 4.27 | 4.27 |
| 412.42 | 3.92 | 3.92 |
| 440.43 | 3.82 | 3.82 |
| 467.29 | 4.92 | 4.92 |
| 454.46 | 4.21 | 4.21 |
| 403.44 | 4.68 | 4.68 |
| 389.41 | 4.59 | 4.59 |
| 375.38 | 4.41 | 4.41 |
| 403.44 | 4.68 | 4.68 |
| 398.40 | 3.61 | 3.61 |
| 389.41 | 4.59 | 4.59 |
| 416.39 | 3.75 | 3.75 |
| 403.44 | 4.68 | 4.68 |