Basic Information
ID: ALA4722526
Type: Binding
Description: Inhibition of Leishmania donovani MetAP1 expressed in Escherichia coli BL21 (DE3) using L-methionine-4-methyl-coumary1-7-amide as substrate preincubated for 30 mins followed by substrate addition and measured at 1 min interval for 30 mins by spectrofluorometric method
Organism: Leishmania donovani
Activity Charts
Bioactivity
Activity Types for Assay ALA4722526
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.38 | 3.86 | 3.86 |
| 412.47 | 3.74 | 3.74 |
| 352.42 | 3.73 | 3.73 |
| 356.83 | 4.37 | 4.37 |
| 401.29 | 4.48 | 4.48 |
| 401.29 | 4.48 | 4.48 |
| 352.42 | 3.73 | 3.73 |
| 352.42 | 3.73 | 3.73 |
| 347.40 | 3.59 | 3.59 |
| 382.44 | 3.74 | 3.74 |
| 336.42 | 4.03 | 4.03 |
| 336.42 | 4.03 | 4.03 |
| 364.47 | 4.84 | 4.84 |
| 322.39 | 3.72 | 3.72 |
| 382.44 | 3.74 | 3.74 |
| 406.39 | 4.62 | 4.62 |
| 414.49 | 5.51 | 5.51 |
| 340.38 | 3.86 | 3.86 |
| 390.39 | 4.74 | 4.74 |
| 448.29 | 4.32 | 4.32 |