Assay Report Card

Basic Information

ID: ALA4722528

Type: Binding

Description: Competitive inhibition of Leishmania donovani MetAP1 expressed in Escherichia coli BL21 (DE3) at 1 to 10 uM using varying levels of L-methionine-4-methyl-coumary1-7-amide as substrate preincubated for 30 mins followed by substrate addition and measured for 30 mins by Lineweaver-burk plot analysis

Organism: Leishmania donovani

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
356.834.374.37
347.403.593.59
336.424.034.03