Assay Report Card

Basic Information

ID: ALA4722620

Type: Binding

Description: Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 assessed as residual activity at 50 uM using 4-hydroxyphenyl pyruvic acid as substrate preincubated for 15 mins followed by substrate addition and measured for 10 mins in presence of 0.5 mM EDTA by UV absorbance analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
273.383.883.88
283.291.231.23
312.302.042.04
347.382.312.31
340.342.242.24
298.282.362.36
241.292.322.32
203.251.931.93
290.280.270.27
261.281.471.47
231.302.712.71
295.301.811.81
243.313.023.02
363.172.262.26
300.341.961.96
280.292.232.23
333.352.382.38
203.252.102.10
298.282.362.36
191.190.470.47
294.311.901.90
244.250.870.87
205.221.031.03
308.342.542.54
314.372.272.27